ASSOCIATION BETWEEN ADVERSE CHILDHOOD EXPERIENCES AND SUBSTANCE USE DISORDERS IN ADULTHOOD
Keywords:
Substance use disorder, Adverse Childhood Experience, ResilienceAbstract
 Adverse Childhood Experiences (ACEs) are potentially traumatic life experiences occurring before the age of 18 years and have tremendous negative impacts on the health and wellbeing of their victims. The study sought to examine the relationship between adverse childhood experiences and the occurrence of substance use disorder in adult life.A case-control study was employed in the study. One hundred and ninety patients diagnosed with substance use disorders comprised the cases, and 190 patients who had no substance use disorder and were the controls. Adverse Childhood Experiences international questionnaire and the Connor-Davidson Resilience Scale were used to obtain information on adverse childhood adversities and resilience respectively. The null hypothesis states that there is no significant association between ACE and substance use disorders. The hypothesis was tested using bivariate and multivariate analysis at 0.05 significant level. The cases had significantly higher proportion of exposure to adverse childhood adversities in comparison to the controls [48.4%(n=92) versus 25.8 %(n=49);p=0.0001)]. The odds of exposure to adverse childhood adversities were two times higher among cases than controls after controlling for socio-demographic variables (Adjusted OR-2.320; 95%CI: 1.44-3.75). Adverse childhood experience is associated with the occurrence of substance use disorders in adulthood irrespective of socio-demographic characteristics. Thus, public health enlightenment to family and schools are hereby advocated.ÂReferences
Aloba, O., Olabisi, O., & Aloba, T. (2016). The 10-Item Connor–Davidson Resilience Scale. Journal of the American Psychiatric Nurses Association, 22, 43–51. https://doi.org/10.1177/1078390316629971
Amaro, H., Sanchez, M., Bautista, T., & Cox, R. . (2021). Social vulnerabilities for substance use: Stressors, socially toxic environments, and discrimination and racism. Neuropharmacology, 188, 108518. https://www.sciencedirect.com/science/article/pii/S0028390821000721
Anda, R. F., Felitti, V. J., Bremner, J. D., Walker, J. D., Whitfield, C., Perry, B. D., Dube, S. R., & Giles, W. H. (2006). The enduring effects of abuse and related adverse experiences in childhood: A convergence of evidence from neurobiology and epidemiology. European Archives of Psychiatry and Clinical Neuroscience, 256, 174–186. https://doi.org/10.1007/s00406-005-0624-4
Federal Republic of Nigeria. (2003). Child Rights Act. Nigeria
First, M. B., Williams, J. B. W., Karg, R. S., & Spitzer, R. L. (2015). Structured clinical interview for DSM-5–Research version (SCID-5-RV, Version 1.0. 0). Arlington: American Psychiatric Association.
Hardt J. R. M. (2004). Validity of adult retrospective reports of adverse childhood experiences: Review of the evidence. Journal of Child Psychoogy and Psychiatry, 45, 260–273.
Humeniuk, R., Ali, R., Babor, T. F., Farrell, M., Formigoni, M. L., Jittiwutikarn, J., De Lacerda, R. B., Ling, W., Marsden, J., Monteiro, M., Nhiwatiwa, S., Pal, H., Poznyak, V., & Simon, S. (2008). Validation of the alcohol, smoking and substance involvement screening test (ASSIST). Addiction, 103(6), 1039–1047. https://doi.org/10.1111/J.1360-0443.2007.02114.X
Ige, O. K., Illesanmi, O. S., Adebayo, A. M. (2012). Sexual Risk Behaviours among Young People with Adverse Childhood Experiences in Ibadan, Nigeria. Greener Journal of Medical Sciences,2(3),70-76.
Kane, J. C., Murray, L. K., Bass, J. K., Johnson, R. M., & Bolton, P. (2016). Validation of a substance and alcohol use assessment instrument among orphans and vulnerable children in Zambia using Audio Computer Assisted Self-Interviewing (ACASI) HHS Public Access. Drug and Alcohol Dependence, 166, 85–92. https://doi.org/10.1016/j.drugalcdep.2016.06.026
Kazeem, O. T. (2015). A Validation of the Adverse Childhood Experiences Scale in Nigeria. Research on Humanities and Social Sciences, 5(11), 2224-5766.
Kiburi, S. K.., Molebatsi, K.., Obondo A., & Kuria, M. (2018). Adverse childhood experiences among patients with substance use disorders at a referral psychiatric hospital in Kenya.BMC Psychiatry 18, 1–12.
Meinck F, Cosma AP, Mikton C, B. A. (2017). Psychometric properties of the Adverse Childhood Experiences Abuse Short Form (ACE-ASF) among Romanian high school students. - PubMed - NCBI. Child Abuse Negl, 72, 326–337.
Monnat, S. M., & Chandler, R. F. (2015). Long-Term Physical Health Consequences of Adverse Childhood Experiences. Sociological Quarterly, 56(4), 723–752. https://doi.org/10.1111/TSQ.12107
Murtha, T. (2018). Screening Adults with Substance Use Disorder for Adverse Childhood Experiences.ScholarWorks UMass.
Naal, H., El Jalkh, T., & Haddad, R. (2018). Adverse childhood experiences in substance use disorder outpatients of a Lebanese addiction center. Psychology, Health and Medicine, 23(9), 1137–1144. https://doi.org/10.1080/13548506.2018.1469781
Navarro-Mateu, F., Quesada, M. P., Escámez, T., Alcaráz, M. J., Seiquer De La Peña, C., Salmerón, D., Huerta, J. M., Vilagut, G., Chirlaque, M. D., Navarro, C., Husky, M., Kessler, R. C., Alonso, J., & MartÃnez, S. (2019). Childhood adversities and 5-HTTLPR polymorphism as risk factors of substance use disorders: Retrospective case-control study in Murcia (Spain). British Medical Journal, 9(9),1. https://doi.org/10.1136/bmjopen-2019-030328
Oladeji, B. D., Makanjuola, V. A., & Gureje, O. (2010). Family-related adverse childhood experiences as risk factors for psychiatric disorders in Nigeria. British Journal of Psychiatry, 196(3), 186–191. https://doi.org/10.1192/bjp.bp.109.063677
Oluwagbemiga, O., & Micheal, J. (2018). Childhood Adversity and Factors Determining Resilience among Undergraduate Students. International Journal of Emergency Mental Health and Human Resilience, 20(2), 1–9. https://doi.org/10.4172/1522-4821.1000400
Rothman, E. F., Edwards, E. M., Heeren, T., & Hingson, R. W. (2008). Adverse Childhood Experiences Predict Earlier Age of Drinking Onset: Results From a Representative US Sample of Current or Former Drinkers What’s Known on This Subject. Pediatrics,122(2), e298–e304. https://doi.org/10.1542/peds.2007-3412
Salawu, M. M., & Owoaje, E. (2015). Adverse Childhood Experiences and Smoking among Urban Youths in Oyo State, South Western Nigeria.ISDS 2013 Conference Abstracts,1–2. https://doi.org/10.5210/ojphi.v6i1.5020
UNICEF. (2019). Adverse Childhood Experiences Research in Serbia (ACE study). UNICEF Serbia, 1–110.
Warne, D., Dulacki, K., Spurlock, M., Meath, T., Davis, M. M., Wright, B., & McConnell, K. J. (2017). Adverse Childhood Experiences (ACE) among American Indians in South Dakota and Associations with Mental Health Conditions, Alcohol Use, and Smoking. Journal of Health Care for the Poor and Underserved, 28(4), 1559–1577. https://doi.org/10.1353/hpu.2017.0133
Whiteford, H. A., Ferrari, A. J., Degenhardt, L., Feigin, V., & Vos, T. (2015). The global burden of mental, neurological and substance use disorders: An analysis from the global burden of disease study 2010. PLoS ONE, 10(2). https://doi.org/10.1371/journal.pone.0116820
World Health Organization (WHO). (2019). Adverse Childhood Experience-International Questionnaire. WHO Publications. https://www.who.int/publications/m/item/adverse-childhood-experiences-international-questionnaire-(ACE-IQ)
Yeoman, K., Safranek, T., Buss, B., Cadwell, B. L., & Mannino, D. (2013). Peer reviewed: adverse childhood experiences and adult smoking, Nebraska, 2011. Preventing chronic disease, 10, E159.
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